Based on The Author’s US Provisional Patent 60/496, 397
INTRODUCTION:
Type 2 diabetes is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and a relative lack of insulin. This discovery is concerned with the relative lack of insulin.
Proposed Pathophysiology of Type 2 Diabetes:
When chromium chloride is proposed to partially release from voltage-gated calcium channels in pancreatic beta cells, due to genetic vulnerability, obesity, oxidative
stress, aging, eating habits, lifestyle and lack of exercise, their threshold becomes low. So the duration of their activation decreases, they will repolarize and inactivate on a current before rest potential current, i.e over - 70 mv. So, voltage-gated calcium channels in pancreatic beta cells close faster than normal and calcium ions influx terminates thus, exocytosis process stops and insulin secretion terminates so, secreted levels of insulin become lower than normal. Thus, type 2 diabetes is predicted to develop. As it is well known, there are grades of diabetes type 2, when the release of chromium chloride is little diabetes type 2 is mild, on the other hand when the release is high, diabetes becomes severe.
CONCLUSION:
Based on our preliminary results – which are consistent with well established scientific
literature - chromium
supplements serve as a long-term and intermittent adjuvant approach that may lower glucose levels
and retard the progression of type 2 diabetes. Via elevation of inactivation
threshold of voltage-gated calcium
channels in pancreatic beta cells thus, enhancing insulin secretion. Daily dose 200 mcg orally for a limited period
of 12 weeks for adults along with
standard treatment, preferably under
medical supervision. Finally, we highly recommend intermittent chromium supplementation for type 2 diabetics and prediabetics.
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* This
discovery does not endorse any product, it is for the sake of patients all over
the world.
* A daily dose of 1000 mcg of chromium compounds for six
months or more may lead to
kidney failure.
kidney failure.
